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Potential Interactions Between Rybelsus and Levothyroxine There is a documented pharmacokinetic interaction between Rybelsus and levothyroxine

doi: 10.1016/j.cmet.2014.02.007 106 MinokoshiYAlquierTFurukawaHKimYBLeeAXueBet al

Among 1961 patients without T2DM in the STEP 1 trial, the mean reduction in body weight from baseline was 14.9% and 2.4% at 68 weeks of follow-up in patients treated with semaglutide 2.4 mg and placebo, respectively ( P 1 weight reported during the 30-day window for a given follow-up time point, the closest weight to the time point of interest was utilized

Individual metabolism: People with faster metabolism tend to metabolize semaglutide faster than others

Bagust A, Beale S

Take home message You can take Mounjaro after gallbladder removal