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Treg cells could not only interact with microglia (75), but also regulate their polarization from M1 to M2 via IL-10 pathway (80, 81)

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it is the reason that in the literature GHK-Cu is linked specifically to matrix and collagen signalling, and not to the routes of ordinary peptides without a metal ion

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561 fludrocortisone, a mineralocorticoid that promotes sodium and water retention to expand plasma volume, though it must be used cautiously due to the risk of supine hypertension and hypokalemia

The strongest evidence comes from preclinical (animal and cell) studies for example BPC-157 accelerated tendon healing 6080% in rat models but human clinical trials remain scarce or absent