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We assessed heterogeneity between the included studies using the I statistic, where I 2 values of 25%, 50%, and 75% indicated low, medium, and high heterogeneity, respectively

A.BossJ.GodwinC.MukherjeeB.FeldmanE

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A randomized add-on trial of an N -methyl-D-aspartate antagonist in treatment-resistant bipolar depression

Develop multitarget drugs that target multiple metabolic processes, such as glucose metabolism, lipid metabolism, and protein metabolism, while simultaneously regulating multiple key enzymes or signaling pathways