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Pownall HJ, et al
Reports of prolonged, heavy, and painful periods are strikingly common across Reddit discussions
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Many patients arrive after reading about tirzepatide or semaglutide and wanting a local provider who will actually examine them, draw labs, and follow their case in person rather than issue a prescription through a questionnaire
PEM, also called Post-Effort Symptom Exacerbation (PESE) (265), can be best evidenced and provoked by two CardioPulmonary Exercise Test (CPET) 24 hours apart