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The patches reduced body weight in the animal model by suppressing appetite and enhancing metabolic rate (8)

For patients with type 2 diabetes who start above an HbA1c of 8%, that level of reduction can translate to a clinically significant lower risk of microvascular complications over time

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When applied to patients, SPECT (single photon emission computed tomography) and PET should be helpful in linking changes occurring in behavior with brain structural/functional changes

Muscle biopsy and histochemistry Open skeletal muscle biopsy was performed in all patients

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