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Dietary modifications can substantially reduce diarrhea symptoms: Eat smaller, more frequent meals rather than large portions Reduce intake of high-fat, greasy, or fried foods, which are harder to digest with delayed gastric emptying Limit foods known to trigger diarrhea, including caffeine, alcohol, artificial sweeteners, and spicy foods Increase soluble fiber intake gradually (oats, bananas, applesauce) while avoiding excessive insoluble fiber during acute symptoms Stay well-hydrated with water and electrolyte-containing beverages Symptomatic management may include over-the-counter antidiarrheal medications such as loperamide (Imodium), though patients should consult their healthcare provider before starting these agents

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however, it may also affect patients with type 2 diabetes ( Case presentation The patient, 36-year old man with new onset of diabetes mellitus, was initially admitted to the Department of Diabetology due to markedly elevated blood glucose levels (277 mg/dl, 15.4 mmol/l), glucosuria, trace amounts of acetone in the urine and with normal arterial blood gas findings

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doi: 10.1016/j.neuropharm.2014.04.007 19 XuMWuHYLiuHGongNWangYRWangYX