Indicative improvement of more than 20% Reduction in autoimmune diseases such as IBS and rheumatoid arthritis Improved mental health Improved cognitive skills Reduced polycystic ovary syndrome with restoration of fertility
In a small pilot study of 6 healthy volunteers who were undergoing screening colonoscopy, patients who received PEG in addition to 10 grams of vitamin C had 35% greater stool volume compared to those who had the standard of care PEG alone (2.2 L vs
And with oral pills now hitting the market (the Wegovy pill got FDA approval in December 2025, with Eli Lillys orforglipron expected to follow in 2026) that curve is only going to steepen
Aim for 0.3-0.5g per pound of body weight
The primary one is competition from other GLP-1 drugs, especially from Eli Lillys Mounjaro (tirzepatide), which has shown greater efficacy in weight loss and diabetes control
Even then, the drugs didnt meet the cost-effectiveness threshold. That threshold is typically defined as less than $100,000 per quality-adjusted life year (QALY) a standard tool health economists use to compare the value of medical treatments