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The terms of the agreement will see Novo paying up to $600 million in upfront, development and commercial milestone payments, as well as tiered royalties on annual net sales of licensed products, to be shared between Metaphore and Flagship

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Its ability to reduce inflammation and support tissue repair extends to the central nervous system, opening avenues for exploring its therapeutic potential in neurological conditions

The authors gratefully acknowledge the support of the patients and medical staff of Golestan Hospital who volunteered to contribute to this study