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Specifically, GLP-1Rs on vagal afferent neurons have been shown to contribute to the incretin effects of GLP-1 shortly after a meal, gastric emptying, and glycemia (Krieger et al., 2015)

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It's important to note that gastrointestinal side effects, including nausea and vomiting, are common with medications that affect GLP-1 pathways

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Scientists are also investigating additional multi-receptor peptides, novel signaling pathways, and advanced molecular structures that may further expand understanding of metabolism and physiological regulation

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