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For diabetes, you must try metformin plus one other oral agent for 90 days each before GLP-1 approval

Obesity, diabetes, and liver disease in relation to cardiovascular risk

How GLP-1 medications impact appetite One of the things that makes GLP-1 medications so effective in helping clients achieve their weight loss goals is how they impact appetite

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References Bowers et al (1992), The growth hormone-releasing activity of a synthetic hexapeptide in normal men and short-statured children after oral administration