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Funding/Conflict: Public Funding: From the study, no public funding was reported
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NAD levels naturally decline with age, dropping sharply in the skin and steadily in the brain, which can affect everything from cellular repair and collagen production to energy, cognition and overall longevity
Additionally, new research indicates that tirzepatide potentially has some advantages over traditional metabolic regulation, such as insulin sensitivity improvement and anti-inflammatory effect [2]
LDL cholesterol dropped by approximately 20% , which is mechanistically unusual for a GLP-1-class compound