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As well, in real-world scenarios, such as described by Brindisi et al, it is mentioned a reduction in pleasure and taste perception in overweight and people with obesity with poor type 2 diabetes control, probably by lowering the detection threshold of sweet flavors, becoming more sensitive to them, resulting in aversion for this flavor (175)

Body mass index, diabetes, and the risk of Parkinsons disease

Roy Chowdhury SK, Sangle GV, Xie X, Stelmack GL, Halayko AJ, Shen GX

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GLP-1, a product of the glucagon gene, is produced in L-cells of the small intestine

Discuss side effects (nausea, vomiting, diarrhea) and realistic expectations: improvement, not elimination of risk