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This might explain the common x axis intercept in LineweaverBurk plots 11,17,18 , which resemble a non-competitive inhibition pattern with identical dissociation constants for the inhibitor and substrate 52
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Clinical trials[1] reveal that tirzepatide can achieve up to 22% body weight reduction and over 2% absolute HbA1c improvement, results unmatched by any previous incretin-based therapy
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