Given that depletion of RNF4 also sensitizes AML cells to replicative stress, targeting of RNF4 could be generally beneficial in tumors with a high replication stress
Association of chronic fatigue syndrome with human leucocyte antigen class II alleles
Consult physician if pregnant/nursing, taking medication, or have a medical condition (especially glaucoma)
Side effects are rare but may include mild fatigue, light nausea, or a slight headache
If you have concerns, discuss them with a healthcare professional who can help determine if glutathione IV is safe and appropriate for your particular health profile
doi:10.4021/JEM.V3I1-2.157 Heffernan M, Summers RJ, Thorburn A, et al