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Despite these promising developments, GLP-1 therapies remain relatively new

The study also noted that B420 increased the abundance of Akkermansia muciniphila in participants' gut microbiota and increased fecal SCFA concentrations including butyric acid, which has been shown to stimulate GLP-1 secretion from intestinal L-cells

Most side effects follow a predictable pattern

Diabetes and cancer: 5 years into the recent controversy

Obesity treatments have been challenging, however, approval of Semaglutide or Wegovy, is a huge step in treatment of obesity

The bottom line suggests that there is some variation in GLP-1 secretion and that in some cohorts, on balance, the GLP-1 response is somewhat reduced, whereas in other studies such differences are not as apparent (Fig