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Gastrointestinal issues were the most common side effects, though the rates of serious adverse events and deaths were similar between the two treatment groups
Bolaman Z, Kadikoylu G, Yukselen V et al
Thyroid function testing, including thyroid-stimulating hormone (TSH) and free thyroxine (T4) levels, should be considered if cold intolerance is severe or accompanied by other hypothyroid symptoms
Ali says this is simply good news for people with type 2 diabetes, overweight, or obesity who also have depression or anxiety
Further translational research and prospective clinical trials are required to clarify causality, determine effect size, and identify high-risk groups most likely to benefit
This gap between expectations and reality is one of the leading drivers of negative reviews
