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"Developing potential therapies that can be administered less frequently could benefit societies, as well as individual patients, and it is a clear focus area for Novo Nordisk," said Brian Vandahl, the company's head of global research technologies

Consistent with the FAP-based approach, stimulation with PF-06882961 for 30 minutes triggered marked intracellular accumulation of GFP-GLP-1R, which was reversible following a 2-hour washout period