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Patients: A total of 822 adult patients with inadequately controlled T2D (A1C 7.0%-10.5%) and receiving a stable dose of metformin were randomized to semaglutide tablets 14 mg (n=412) or Jardiance 25 mg (n=410), both once daily
On this final point, it bears note that a Phase III clinical trial recently found that 50mg oral semaglutide tablets achieved superior weight loss in adults with obesity compared with placebo
Its hydrophobic nature and low aqueous solubility result in poor absorption, which constrains its topical efficacy
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C., Suhandi, C., Afidika, J., Ghaliya, S., Elamin, K
doi: 10.1136/gutjnl-2020-323082 7
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