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The escalation typically started at 2 mg weekly for the first 4 weeks, then increased every four weeks in increments of 2 to 4 mg until the target research dose was reached

Data are representative of minimum three independent experiments and the number of biological replicates is quoted in the figure legends

Maintains the well-being of the liver and prevents the destruction of the liver by toxins, such as acetaminophen poisoning

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Hydrogel homogenate production/protein binding Hydrogels were made by adding 150 L PEGDA (MW 575, Sigma Aldrich) to varying concentrations of glutathione (Sigma Aldrich, Alfa Aesar) and 0.05% w/v Irgacure 2959 (Ciba)