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Hasan M, Messaoud GB, Michaux F, Tamayol A, Kahn CJ, Belhaj N, Linder M, Arab-Tehrany E

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However, even with excellent support, maintaining weight loss without medication is achievable for only about 2030% of patients who initially lost significant weight on GLP-1 therapy

Fluid Retention and Heart Failure with Concomitant Use of PPAR-gamma Agonists: Fluid retention and heart failure can occur with concomitant use of thiazolidinediones (TZDs), which are PPAR-gamma agonists, and insulin, including Tresiba

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