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Despite the short plasma half-life, downstream biological effects in tissue persist substantially longer, consistent with a signaling cascade rather than direct dose-response activity

Vieta E, Valent M

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State and federal policymakers are increasingly responding to the issue, including new legislation introduced in Kentucky following a case in which a patient suffered acute liver failure requiring a transplant after taking a compounded weight-loss medication

D., Chen, K.-H., & Chen, C