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The increased prevalence of comorbidities and polypharmacy in elderly patients necessitates careful monitoring during dose escalation

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Initially focusing on specific subsets of cardiomyocytes, they identified a cluster labeled aCM2 present in YAP5SA-expressing adult and neonatal hearts but absent in non-regenerative adult mouse hearts

Sensitivity analyses To quantify the effects of uncertainty in the input variables on the results, we performed one-way sensitivity analyses using the lower and upper bounds outlined in Table 1