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SGLT-2 inhibitors (like empagliflozin and dapagliflozin) increase urinary glucose levels, creating conditions that promote bacterial growth and have documented associations with UTIs and genital infections

For those interested in topical application methods , concentrations and formulation details matter significantly for outcomes

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For weight management, NICE recommends these medications as an adjunct to lifestyle modification in specialist weight management services, with specific BMI thresholds (typically 35 kg/m or 32.5 kg/m in certain ethnic groups) with comorbidities, and usually for time-limited periods (up to 2 years for semaglutide)