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Current therapies include limiting absorption of APAP by administering activated charcoal 8,9,10 , replenishing glutathione stores by administering the glutathione precursor n -acetylcysteine (NAC) 11,12 , the JNK/CYP2E1 inhibitor fomepizole ( 13 ), and supportive care

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Individual Factors Affecting Requirements Age, stress levels, environmental exposure, exercise intensity, and overall health status all influence glutathione requirements

Zordoky BN, Sung MM, Ezekowitz J, Mandal R, Han B, Bjorndahl TC, et al