Exenatide remains effective but is generally less potent in both glycemic and weight outcomes, which has limited its current use (Thomsen et al., 2025)
Here is a nice comparison table and some nuggets to think about
This class includes semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)
The abdomen provides the most accessible location for self-injection, with the area 2 or more inches from the navel offering appropriate subcutaneous tissue depth
Cost & Convenience Oral supplements are cheaper, widely available over-the-counter, and more convenient
The medication is administered as a once-weekly subcutaneous injection, starting with a non-therapeutic initiation dose of 0.25 mg for 4 weeks, then titrating to maintenance doses of 0.5 mg, 1 mg, or 2 mg depending on individual response and tolerability