Tirzepatide with B12 looks almost indistinguishable from semaglutide with B12, assuming similar B12 concentrations
Gastrointestinal Adverse Reactions In the pool of placebo-controlled trials, gastrointestinal adverse reactions occurred more frequently among patients who received semaglutide tablets than placebo: semaglutide tablets 14 mg once daily (41%), semaglutide tablets 7 mg once daily (32%) and placebo (21%), including severe reactions (semaglutide tablets 14 mg 2.0%, semaglutide tablets 7 mg 0.6%, placebo 0.3%)
Can we save these cases
Any protective effects of these medications differ at different levels of addiction severity, though their medical record-based outcomes were likely capturing people with more severe opioid and alcohol use disorder, since they were presenting to clinics and hospitals with alcohol intoxication and opioid poisoning
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I am not going bonkers, and i did in fact, find some studies which do indicate/confirm that we store B12 other than in the Liver - See my response below