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In addition, adipose tissue secretes proinflammatory cytokines, including tumor necrosis factor- (TNF-) and interleukin-6 (IL-6), which may impair neuromuscular control and exacerbate nocturnal respiratory instability (9, 10)

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Earlier this month, the FDA announced plans to limit the ingredients used in these compounded products and to step up enforcement against their marketing, noting that the agency cannot verify their quality or effectiveness

Moreover, as new indications are approved, avoiding unintentional duplicate therapy is essential

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