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Home Injection (with Prescription): Suitable for long-term users trained in safe injection technique

Based on GLP-1 nasal delivery research, intranasal retatrutide would likely require daily or multiple-times-daily administration

This means subcutaneous injections are often used when other administration methods might be less effective

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For weight management, only semaglutide (Wegovy) and liraglutide (Saxenda) are licensed, with specific eligibility criteria outlined in NICE guidance