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Luan et al., 2021
Materials and Methods: A TS model rat was established through intraperitoneal administration of 3,3-Iminodipropionitrile (150 mg/kg/day), followed by GABA (20 mg/kg/day) administration by gavage
Even if each peptide has independent research support, the combination has not been studied for synergy, antagonism, pharmacokinetic interaction, or safety
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
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