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Additionally, GLP-1RAs protect against CVD by improving endothelial dysfunction, an early phase of atherosclerosis [28,29], triggered by high blood pressure, diabetes, and elevated cholesterol [30,31]

Important safety considerations include risks of acute pancreatitis (seek medical attention for severe abdominal pain with or without vomiting), gallbladder disease, dehydration, and potential worsening of diabetic retinopathy with rapid improvement in glucose control

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found that melanotan II reversed autistic features in a maternal immune activation (MIA) mouse model of autism