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In addition, hyperandrogenism by itself stimulates the deposition of adipose tissue in the visceral area, with further increase in insulin resistance, thus contributing to the vicious circle [17]
The strongest evidence-based case for GLP-1 therapy is in patients who have both overweight or obesity and established cardiovascular disease
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The three phases are activation in weeks 14, remodeling in weeks 58, and maintenance in weeks 912
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