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However, whilst multiple compounds targeting redox regulation have been reported to slow disease progression in SOD1 G93A mice (Dash et al., 2018), they have subsequently failed to enhance survival or improve motor function in ALS patients in clinical trials
However, the fact that AOXs are largely available over-the-counter with a reasonable price increases the risk that some patients can overmedicate with AOXs leading to detrimental effects
Recent studies have underscored its significant relationship with OA, demonstrating iron accumulation and lipid peroxidation in osteoarthritic cartilage [22,23]
Protoplasma 240 , 312 (2010)
And the reason it gets produced most abundantly is because it does two things very effectively for us
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