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Your prescriber or pharmacist is the right source for how to space your particular medications

Use sparingly and massage into area to be treated

New England Journal of Medicine, 375(19), 1834-1844

When it works, the enhanced weight loss and improved metabolic markers make it worth considering as a first-line option

Available from Accessed 21 Feb 2020 Inzucchi SE, Bergenstal RM, Buse JB et al (2015) Management of Hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes

2 NICE recommends reviewing treatment if less than 5% of body weight has been lost after 6 months on the highest tolerated dose