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Drugs are not metabolized by the liver, but multidrug and toxin extrusion protein 1 (MATE1) expressed in hepatocytes is involved in the clearance of drugs, which is transported to the kidney through bile or through blood (Gong et al., 2012)

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Exogenous GH administration reduces total body fatparticularly abdominal and visceral fatby increasing fat oxidation and energy expenditure. Johannsson, G

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