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28 PKA goes on to phosphorylate cAMP response element binding protein (CREB), a transcription factor that turns on genes that make neurotrophic factors and anti-apoptotic proteins

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Nevertheless, the improvement in lipid tolerance was similar in mice receiving the 2 different doses of sitagliptin (Figure 1C), highlighting the importance of DPP-4 + cells within the gut for control of lipid tolerance

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