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Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state

Proven results backed by scientific studies

Not intended for in vivo applications

These alterations contribute to mitochondrial dysfunction, insulin resistance (IR), and the pathogenesis of sarcopenia [39, 81]

The evolving paradigm of obesity treatment necessitates reconsideration of intervention timing, specifically for GLP-1 non-responders who show minimal early progress

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