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P., Francomano, C

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Although uncommon, possible side effects of such a high-dose B-12 include acne and rosacea, and one study found high-dose B-12 to increase the risk of colorectal cancer in older adults when also given with folate (which is also in the product)

2013;28(2):33744 Thomas MC, Forbes JM, Cooper ME

CoQ10, muscle symptoms and mitochondria Muscle symptoms (SAMS statin-associated muscle symptoms) feel very real for patients, even though large trials suggest that only a smaller fraction of muscle pain in statin users is directly caused by the drug

There is a registry for women who become pregnant during treatment with FIRDAPSE