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The unamidated free-carboxylic-acid form binds with substantially reduced affinity and produces a different downstream signalling profile in cell-based assays

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Pharmacies offer them

For many patients, their injections dont last long enough Some clinicians assume (incorrectly) that 1000 mcg of B12 should last patients at least 200 days, calculating from a 5 mcg daily requirement for the vitamin

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