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Natural DPP4 inhibitors: Research shows that several herbal supplements, including resveratrol, luteolin, and apigenin, inhibit DPP4

(2004), Abu-Elheiga et al

In a large Phase 3 clinical trial (STEP series), semaglutide demonstrated excellent weight loss and weight maintenance after weight loss

For people with hyperthyroidism or Graves' disease, GLP-1 use must be discussed carefully with an endocrinologist, as rapid weight loss in the setting of elevated thyroid hormone can increase metabolic stress

Accessed Dec 2024

In the hindbrain, the dorsal-vagal-complex (DVC), collectively comprised of the nucleus tractus solitarius (NTS), area postrema (AP) and dorsal motor nucleus of the vagus (DMV), mediates the anorectic effects of both amylin and GLP-1 receptor agonists 15,16,17,18,19