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Some experimental results suggest significant increases in circulating IGF-1, which is thought to act as a downstream mediator of growth hormone activity

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A total of 938 subjects with a mean baseline body weight of 100.7 kg and a baseline A1C of 8.0% were enrolled in the study

10.1155/2017/9747256 Biomed Res Int

These include autoimmune conditions, Parkinson's disease, Alzheimer's disease, and cancer