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The black curve shows the response of the male to an 18-gm dose of APAP if not treated

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Peripheral-central neuroimmune cross talk The status of barrier protection in PD The BBB, the blood-cerebrospinal fluid barrier (BCSFB) and the meninges are critical gatekeepers that regulate the passage of substances between the systemic circulation and the CNS

Chaffei C, Pageau K, Suzuki A, Gouia H, Ghorbel MH, Masclaux-Daubresse C (2004) Cadmium toxicity induced changes in nitrogen management in Lycopersicon esculentum leading to a metabolic safeguard through an amino acid storage strategy