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Support for Lean Mass Preservation While promoting fat loss, Retatrutides balanced metabolic action may help maintain lean muscle mass, especially when combined with lifestyle interventions like diet and resistance training

Semaglutide belongs to a class of drugs called glucagon-like peptide-1 receptor agonists, or GLP-1 RAs

We furthermore thank Luise Krauth-Siegel for helpful discussions and Tobias Dick and Bruce Morgan for reading an initial version of the manuscript and suggestions

Fat loss depends on energy deficit only, independently of the method for weight loss

Berndt, C., Schwenn, J

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