Document the Open Date: For multi-use vials, use a permanent marker to write the date you first punctured the stopper on the label
Drink water steadily through the day even when you do not feel thirsty, and contact your doctor about dark urine, extreme tiredness, or increased confusion
Oral semaglutide ($289/month) and oral tirzepatide ($349/month) may feel gentler on the GI tract than injections because they bypass initial rapid systemic absorption, though oral bioavailability is lower and requires strict fasting administration
Furthermore, work in an cellspecific PC1/3KO mouse model demonstrates that loss of cellderived GLP-1 impairs the response to metabolic stress (20)
If changing the weekly administration day, ensure the new injection is given at least 72 hours after the last dose
PJ: is an employee of Novo Nordisk A/S