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Potentially the lung may be utilizing GSH from the plasma through an intact uptake mechanism shown to occur in the lung [27], which is then apically transported into the ELF, resulting in no net change in lung tissue GSH but a drastic increase in ELF GSH

While the mid-regions of both peptides interact with the top of TM1/ECD stalk, the ECD, ECL1 and the top of TM2, exendin-4 exhibits more persistent interactions in the simulations, particularly with the TM1/stalk and ECD (Supplementary Tables 1 and 3)

References Smith J, et al

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