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te Koppele JM et al
Many patients notice pain relief and increased function within weeks, with additional improvement over a few months
In aged rat models, treatment increased activity of antioxidant enzymes like superoxide dismutase (SOD), glutathione peroxidase, and glutathione-S-transferase, improving overall oxidative defense
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This could also address an area of concern for roughly two-thirds of physicians who question whether non-traditional telehealth providers offer sufficient oversight when prescribing GLP-1s , per a December 2025 Sermo survey
However, Medicare Part D can cover these drugs when they're prescribed for a covered medical condition
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