Reported or proposed issue Pregnancy, breastfeeding, children, liver disease, or cancer history Evidence source No direct human safety data Known or theoretical
Up to 50% improvement in cognitive performance and mood-related symptoms has been reported in patients treated with B12 injections, especially in those with mild deficiency
Difficulties with maintaining balance
So the practical takeaway is not oral is better or SC is better. It is: pick one route, follow the documented per-dose figure for the vial you have, and keep the route constant so that whatever you observe is not confounded by a mid-stream route change
The pharmacist can advise whether this is suitable and explain when blood testing or GP input may be needed
Once the B12 is in the muscle, it moves into the bloodstream over the following hours