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Rapid weight reduction alters this hormonal milieu, which can temporarily disrupt the hypothalamic-pituitary-ovarian axis, leading to changes in menstrual patterns
Synaptic plasticity Synaptic plasticity refers to activity-dependent modification of the strength or efficacy of synaptic transmission at pre-existing synapses in response to experiences [171]
The use of GLP-1 agonists has been associated with significant total body weight loss (fat and lean mass), with lean mass representing approximately 25% of total body weight loss [9]
A clinical study concludes that patients showed a mean weight loss of 10-15% or 10 to 15 kg with Wegovy (2.4 mg once weekly) after 68 weeks
Safety events were identified through clinical documentation without independent adjudication
