The C max values of each dose were 1.05 0.429, 3.30 0.508, and 26.1 7.82 ng/ml, respectively, and the AUC 0t values were 29.0 2.68, 160 21.0, and 830 247 ng min/mL respectively
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Measurement of hemodynamic, diuretic and natriuretic responses to GLP-1 Rats were assigned randomly to one of six groups: Sham, Sham + T-RDN, Sham + A-RDN, HF, HF + T-RDN, HF + A-RDN with n = 610/group
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