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Research presented at the 2025 American Academy of Orthopaedic Surgeons meeting found GLP-1 users had approximately 30% higher rates of osteoporosis compared to non-users, and a 2024 phase 2 trial published in eClinicalMedicine showed increased bone resorption markers and lower bone mass at the spine and hip in the semaglutide group versus placebo after 52 weeks
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Tirzepatide certainly affects metabolism in a good way
In addition, a 2024 study found that people taking another GLP-1 drug, liraglutide, had a 179% higher risk of developing NAION
"Delay your shot Im concerned about dehydration in addition to low blood sugars." u/Neat-Tangelo-1749 After speaking with a nurse, the original poster reflected
Specific needs of dopamine neurons for stimulation in order to survive: implication for Parkinson disease
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