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For medical use, see Cyanocobalamin injection for adverse effects and precautions
Wu and Ng addressed this directly in 1993, reporting that a synthetic peptide corresponding to residues 177 to 191 of hGH reproduced the antilipogenic activity of the intact molecule in isolated rat adipose tissue, with a magnitude comparable to the full hormone [1]
These include: Inappropriate dosing or frequency Lack of proper diagnosis and monitoring Non-sterile injection technique increasing infection risk Absence of medical supervision for adverse reactions Financial cost without clinical benefit Patients should report any suspected adverse reactions to B12 injections via the MHRA Yellow Card scheme
Vitamin B12 Deficiency Has Nothing To Do With Weight Gain There is very little evidence to suggest that vitamin B12 affects the process of gaining or losing weight, despite the numerous techniques involved
doi:10.1016/j.clinbiochem.2003.08.004